Cargando…
Antileishmanial High-Throughput Drug Screening Reveals Drug Candidates with New Scaffolds
Drugs currently available for leishmaniasis treatment often show parasite resistance, highly toxic side effects and prohibitive costs commonly incompatible with patients from the tropical endemic countries. In this sense, there is an urgent need for new drugs as a treatment solution for this neglect...
Autores principales: | Siqueira-Neto, Jair L., Song, Ok-Ryul, Oh, Hyunrim, Sohn, Jeong-Hun, Yang, Gyongseon, Nam, Jiyoun, Jang, Jiyeon, Cechetto, Jonathan, Lee, Chang Bok, Moon, Seunghyun, Genovesio, Auguste, Chatelain, Eric, Christophe, Thierry, Freitas-Junior, Lucio H. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864270/ https://www.ncbi.nlm.nih.gov/pubmed/20454559 http://dx.doi.org/10.1371/journal.pntd.0000675 |
Ejemplares similares
-
An Image-Based High-Content Screening Assay for Compounds Targeting Intracellular Leishmania donovani Amastigotes in Human Macrophages
por: Siqueira-Neto, Jair L., et al.
Publicado: (2012) -
An Image-Based Algorithm for Precise and Accurate High Throughput Assessment of Drug Activity against the Human Parasite Trypanosoma cruzi
por: Moon, Seunghyun, et al.
Publicado: (2014) -
Shortening the drug discovery pipeline: small molecule high content screening for lead discovery in neglected disease
por: Cechetto, Jonathan, et al.
Publicado: (2011) -
A high-throughput cell-based assay to screen for drugs affecting PfEMP1 transport to RBC surface
por: Ku, Min-Je, et al.
Publicado: (2011) -
Developments in Diagnosis and Antileishmanial Drugs
por: Bhargava, Prachi, et al.
Publicado: (2012)