Cargando…
Is canalization more than just a beautiful idea?
The heat-shock protein 90 (Hsp90) is currently thought to buffer eukaryotic cells against perturbations caused by pre-existing cryptic genetic variation. A new study suggests that the buffering function of Hsp90 could instead be due to its repression of de novo transposon-mediated mutagenesis.
| Autores principales: | , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864559/ https://www.ncbi.nlm.nih.gov/pubmed/20236474 http://dx.doi.org/10.1186/gb-2010-11-3-109 |
| _version_ | 1782180785841766400 |
|---|---|
| author | Sato, Kaoru Siomi, Haruhiko |
| author_facet | Sato, Kaoru Siomi, Haruhiko |
| author_sort | Sato, Kaoru |
| collection | PubMed |
| description | The heat-shock protein 90 (Hsp90) is currently thought to buffer eukaryotic cells against perturbations caused by pre-existing cryptic genetic variation. A new study suggests that the buffering function of Hsp90 could instead be due to its repression of de novo transposon-mediated mutagenesis. |
| format | Text |
| id | pubmed-2864559 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2010 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-28645592010-05-05 Is canalization more than just a beautiful idea? Sato, Kaoru Siomi, Haruhiko Genome Biol Research highlight The heat-shock protein 90 (Hsp90) is currently thought to buffer eukaryotic cells against perturbations caused by pre-existing cryptic genetic variation. A new study suggests that the buffering function of Hsp90 could instead be due to its repression of de novo transposon-mediated mutagenesis. BioMed Central 2010 2010-03-16 /pmc/articles/PMC2864559/ /pubmed/20236474 http://dx.doi.org/10.1186/gb-2010-11-3-109 Text en Copyright ©2010 BioMed Central Ltd |
| spellingShingle | Research highlight Sato, Kaoru Siomi, Haruhiko Is canalization more than just a beautiful idea? |
| title | Is canalization more than just a beautiful idea? |
| title_full | Is canalization more than just a beautiful idea? |
| title_fullStr | Is canalization more than just a beautiful idea? |
| title_full_unstemmed | Is canalization more than just a beautiful idea? |
| title_short | Is canalization more than just a beautiful idea? |
| title_sort | is canalization more than just a beautiful idea? |
| topic | Research highlight |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864559/ https://www.ncbi.nlm.nih.gov/pubmed/20236474 http://dx.doi.org/10.1186/gb-2010-11-3-109 |
| work_keys_str_mv | AT satokaoru iscanalizationmorethanjustabeautifulidea AT siomiharuhiko iscanalizationmorethanjustabeautifulidea |