Genome-wide DNA demethylation in mammals

The cytidine deaminase AID and elongator-complex proteins contribute to the extensive removal of DNA methylation in mammalian primordial germ cells and in the paternal pronucleus of the zygote.

Detalles Bibliográficos
Autores principales: Sanz, Lionel A, Kota, Satya K, Feil, Robert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864560/
https://www.ncbi.nlm.nih.gov/pubmed/20236475
http://dx.doi.org/10.1186/gb-2010-11-3-110
Descripción
Sumario:The cytidine deaminase AID and elongator-complex proteins contribute to the extensive removal of DNA methylation in mammalian primordial germ cells and in the paternal pronucleus of the zygote.

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