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Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action
We systematically analyzed the relationships between gene fitness profiles (co-fitness) and drug inhibition profiles (co-inhibition) from several hundred chemogenomic screens in yeast. Co-fitness predicted gene functions distinct from those derived from other assays and identified conditionally depe...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864570/ https://www.ncbi.nlm.nih.gov/pubmed/20226027 http://dx.doi.org/10.1186/gb-2010-11-3-r30 |