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Basal core promoters control the equilibrium between negative cofactor 2 and preinitiation complexes in human cells
BACKGROUND: The general transcription factor TFIIB and its antagonist negative cofactor 2 (NC2) are hallmarks of RNA polymerase II (RNAPII) transcription. Both factors bind TATA box-binding protein (TBP) at promoters in a mutually exclusive manner. Dissociation of NC2 is thought to be followed by TF...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864573/ https://www.ncbi.nlm.nih.gov/pubmed/20230619 http://dx.doi.org/10.1186/gb-2010-11-3-r33 |