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Detective quantum efficiency of electron area detectors in electron microscopy
Recent progress in detector design has created the need for a careful side-by-side comparison of the modulation transfer function (MTF) and resolution-dependent detective quantum efficiency (DQE) of existing electron detectors with those of detectors based on new technology. We present MTF and DQE m...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864625/ https://www.ncbi.nlm.nih.gov/pubmed/19497671 http://dx.doi.org/10.1016/j.ultramic.2009.04.002 |
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author | McMullan, G. Chen, S. Henderson, R. Faruqi, A.R. |
author_facet | McMullan, G. Chen, S. Henderson, R. Faruqi, A.R. |
author_sort | McMullan, G. |
collection | PubMed |
description | Recent progress in detector design has created the need for a careful side-by-side comparison of the modulation transfer function (MTF) and resolution-dependent detective quantum efficiency (DQE) of existing electron detectors with those of detectors based on new technology. We present MTF and DQE measurements for four types of detector: Kodak SO-163 film, TVIPS 224 charge coupled device (CCD) detector, the Medipix2 hybrid pixel detector, and an experimental direct electron monolithic active pixel sensor (MAPS) detector. Film and CCD performance was measured at 120 and 300 keV, while results are presented for the Medipix2 at 120 keV and for the MAPS detector at 300 keV. In the case of film, the effects of electron backscattering from both the holder and the plastic support have been investigated. We also show that part of the response of the emulsion in film comes from light generated in the plastic support. Computer simulations of film and the MAPS detector have been carried out and show good agreement with experiment. The agreement enables us to conclude that the DQE of a backthinned direct electron MAPS detector is likely to be equal to, or better than, that of film at 300 keV. |
format | Text |
id | pubmed-2864625 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-28646252010-05-25 Detective quantum efficiency of electron area detectors in electron microscopy McMullan, G. Chen, S. Henderson, R. Faruqi, A.R. Ultramicroscopy Article Recent progress in detector design has created the need for a careful side-by-side comparison of the modulation transfer function (MTF) and resolution-dependent detective quantum efficiency (DQE) of existing electron detectors with those of detectors based on new technology. We present MTF and DQE measurements for four types of detector: Kodak SO-163 film, TVIPS 224 charge coupled device (CCD) detector, the Medipix2 hybrid pixel detector, and an experimental direct electron monolithic active pixel sensor (MAPS) detector. Film and CCD performance was measured at 120 and 300 keV, while results are presented for the Medipix2 at 120 keV and for the MAPS detector at 300 keV. In the case of film, the effects of electron backscattering from both the holder and the plastic support have been investigated. We also show that part of the response of the emulsion in film comes from light generated in the plastic support. Computer simulations of film and the MAPS detector have been carried out and show good agreement with experiment. The agreement enables us to conclude that the DQE of a backthinned direct electron MAPS detector is likely to be equal to, or better than, that of film at 300 keV. Elsevier 2009-08 /pmc/articles/PMC2864625/ /pubmed/19497671 http://dx.doi.org/10.1016/j.ultramic.2009.04.002 Text en © 2009 Elsevier B.V. https://creativecommons.org/licenses/by/3.0/ Open Access under CC BY 3.0 (https://creativecommons.org/licenses/by/3.0/) license |
spellingShingle | Article McMullan, G. Chen, S. Henderson, R. Faruqi, A.R. Detective quantum efficiency of electron area detectors in electron microscopy |
title | Detective quantum efficiency of electron area detectors in electron microscopy |
title_full | Detective quantum efficiency of electron area detectors in electron microscopy |
title_fullStr | Detective quantum efficiency of electron area detectors in electron microscopy |
title_full_unstemmed | Detective quantum efficiency of electron area detectors in electron microscopy |
title_short | Detective quantum efficiency of electron area detectors in electron microscopy |
title_sort | detective quantum efficiency of electron area detectors in electron microscopy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864625/ https://www.ncbi.nlm.nih.gov/pubmed/19497671 http://dx.doi.org/10.1016/j.ultramic.2009.04.002 |
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