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Computational Protein Design: Validation and Possible Relevance as a Tool for Homology Searching and Fold Recognition
BACKGROUND: Protein fold recognition usually relies on a statistical model of each fold; each model is constructed from an ensemble of natural sequences belonging to that fold. A complementary strategy may be to employ sequence ensembles produced by computational protein design. Designed sequences c...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864755/ https://www.ncbi.nlm.nih.gov/pubmed/20463972 http://dx.doi.org/10.1371/journal.pone.0010410 |