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Activation of PERK Signaling Attenuates Aβ-Mediated ER Stress

Alzheimer's disease (AD) is characterized by the deposition of aggregated beta-amyloid (Aβ), which triggers a cellular stress response called the unfolded protein response (UPR). The UPR signaling pathway is a cellular defense system for dealing with the accumulation of misfolded proteins but s...

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Detalles Bibliográficos
Autores principales:	Lee, Do Yeon, Lee, Kyu-Sun, Lee, Hyun Jung, Kim, Do Hee, Noh, Yoo Hun, Yu, Kweon, Jung, Hee-Yeon, Lee, Sang Hyung, Lee, Jun Young, Youn, Young Chul, Jeong, Yoonhwa, Kim, Dae Kyong, Lee, Won Bok, Kim, Sung Su
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864758/ https://www.ncbi.nlm.nih.gov/pubmed/20463975 http://dx.doi.org/10.1371/journal.pone.0010489

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