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Sensitivity of Cancer Cells to Truncated Diphtheria Toxin
BACKGROUND: Diphtheria toxin (DT) has been utilized as a prospective anti-cancer agent for the targeted delivery of cytotoxic therapy to otherwise untreatable neoplasia. DT is an extremely potent toxin for which the entry of a single molecule into a cell can be lethal. DT has been targeted to cancer...
Autores principales: | Zhang, Yi, Schulte, Wendy, Pink, Desmond, Phipps, Kyle, Zijlstra, Andries, Lewis, John D., Waisman, David Morton |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864767/ https://www.ncbi.nlm.nih.gov/pubmed/20463924 http://dx.doi.org/10.1371/journal.pone.0010498 |
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