Cargando…
Magnetic nanoformulation of azidothymidine 5’-triphosphate for targeted delivery across the blood–brain barrier
Despite significant advances in highly active antiretroviral therapy (HAART), the prevalence of neuroAIDS remains high. This is mainly attributed to inability of antiretroviral therapy (ART) to cross the blood–brain barrier (BBB), thus resulting in insufficient drug concentration within the brain. T...
Autores principales: | Saiyed, Zainulabedin M, Gandhi, Nimisha H, Nair, Madhavan PN |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865010/ https://www.ncbi.nlm.nih.gov/pubmed/20463931 |
Ejemplares similares
-
Azidothymidine-triphosphate impairs mitochondrial dynamics by disrupting the quality control system
por: Nomura, Ryosuke, et al.
Publicado: (2017) -
Novel elvitegravir nanoformulation for drug delivery across the blood-brain barrier to achieve HIV-1 suppression in the CNS macrophages
por: Gong, Yuqing, et al.
Publicado: (2020) -
Effects of Treatment with Platinum Azidothymidine and Azidothymidine on Telomerase Activity and Bcl-2 Concentration in Hepatocellular Carcinoma- Induced Rats
por: Sabokrouh, Abdolreza, et al.
Publicado: (2014) -
Comparison between Platinum-Azidothymidine and Azidothymidine Effects on Bcl-2 and Telomerase Gene Expression in Rats with Hepatocellular Carcinoma
por: Sabokrouh, Abdolreza, et al.
Publicado: (2015) -
Targeted Brain Derived Neurotropic Factors (BDNF) Delivery across the Blood-Brain Barrier for Neuro-Protection Using Magnetic Nano Carriers: An In-Vitro Study
por: Pilakka-Kanthikeel, Sudheesh, et al.
Publicado: (2013)