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A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer

Oral cancers are the 11th most common malignancy reported worldwide, accounting for 3% of all newly diagnosed cancer cases, and one with high mortality ratios among all malignancies. The objective of this study was to study the electrical properties of cancerous tongue tissue (CTT) and normal tongue...

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Autores principales: Ching, Congo Tak-Shing, Sun, Tai-Ping, Huang, Su-Hua, Hsiao, Chin-Sung, Chang, Ching-Haur, Huang, Shiow-Yuan, Chen, Yi-Juai, Cheng, Chi-Sheng, Shieh, Hsiu-Li, Chen, Chung-Yuan
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865016/
https://www.ncbi.nlm.nih.gov/pubmed/20463937
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author Ching, Congo Tak-Shing
Sun, Tai-Ping
Huang, Su-Hua
Hsiao, Chin-Sung
Chang, Ching-Haur
Huang, Shiow-Yuan
Chen, Yi-Juai
Cheng, Chi-Sheng
Shieh, Hsiu-Li
Chen, Chung-Yuan
author_facet Ching, Congo Tak-Shing
Sun, Tai-Ping
Huang, Su-Hua
Hsiao, Chin-Sung
Chang, Ching-Haur
Huang, Shiow-Yuan
Chen, Yi-Juai
Cheng, Chi-Sheng
Shieh, Hsiu-Li
Chen, Chung-Yuan
author_sort Ching, Congo Tak-Shing
collection PubMed
description Oral cancers are the 11th most common malignancy reported worldwide, accounting for 3% of all newly diagnosed cancer cases, and one with high mortality ratios among all malignancies. The objective of this study was to study the electrical properties of cancerous tongue tissue (CTT) and normal tongue tissue (NTT). Five tongue cancer patients participated in this study. A disposable probe incorporating four silver electrodes was used to measure the electrical properties of CTT and the surrounding NTT of patients. Measurements were performed at six frequencies: 20 Hz; 50 kHz; 1.3 MHz; 2.5 MHz; 3.7 MHz; and 5 MHz, with the amplitude of the applied voltage limited to 200mV. Four measurement parameters of impedance (Z), phase angle (θ), real part of impedance (R), and imaginary part of impedance (X) of tongue tissue were assessed to see if there was any significant difference in the values obtained in CTT and surrounding NTT. The intraclass correlation coefficient showed that all measurements were reliable. A significant difference (P < 0.05 for the four measurement parameters) was found at 50kHz between CTT and surrounding NTT. It was also found that Z and R of CTT were generally smaller than that of surrounding NTT. In conclusion, bioimpedance at a particular frequency is a potentially promising technique for tongue cancer screening.
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spelling pubmed-28650162010-05-12 A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer Ching, Congo Tak-Shing Sun, Tai-Ping Huang, Su-Hua Hsiao, Chin-Sung Chang, Ching-Haur Huang, Shiow-Yuan Chen, Yi-Juai Cheng, Chi-Sheng Shieh, Hsiu-Li Chen, Chung-Yuan Int J Nanomedicine Original Research Oral cancers are the 11th most common malignancy reported worldwide, accounting for 3% of all newly diagnosed cancer cases, and one with high mortality ratios among all malignancies. The objective of this study was to study the electrical properties of cancerous tongue tissue (CTT) and normal tongue tissue (NTT). Five tongue cancer patients participated in this study. A disposable probe incorporating four silver electrodes was used to measure the electrical properties of CTT and the surrounding NTT of patients. Measurements were performed at six frequencies: 20 Hz; 50 kHz; 1.3 MHz; 2.5 MHz; 3.7 MHz; and 5 MHz, with the amplitude of the applied voltage limited to 200mV. Four measurement parameters of impedance (Z), phase angle (θ), real part of impedance (R), and imaginary part of impedance (X) of tongue tissue were assessed to see if there was any significant difference in the values obtained in CTT and surrounding NTT. The intraclass correlation coefficient showed that all measurements were reliable. A significant difference (P < 0.05 for the four measurement parameters) was found at 50kHz between CTT and surrounding NTT. It was also found that Z and R of CTT were generally smaller than that of surrounding NTT. In conclusion, bioimpedance at a particular frequency is a potentially promising technique for tongue cancer screening. Dove Medical Press 2010 2010-04-07 /pmc/articles/PMC2865016/ /pubmed/20463937 Text en © 2010 Ching et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Original Research
Ching, Congo Tak-Shing
Sun, Tai-Ping
Huang, Su-Hua
Hsiao, Chin-Sung
Chang, Ching-Haur
Huang, Shiow-Yuan
Chen, Yi-Juai
Cheng, Chi-Sheng
Shieh, Hsiu-Li
Chen, Chung-Yuan
A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer
title A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer
title_full A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer
title_fullStr A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer
title_full_unstemmed A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer
title_short A preliminary study of the use of bioimpedance in the screening of squamous tongue cancer
title_sort preliminary study of the use of bioimpedance in the screening of squamous tongue cancer
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865016/
https://www.ncbi.nlm.nih.gov/pubmed/20463937
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