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The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis
The lungs are generated by branching morphogenesis as a result of reciprocal signalling interactions between the epithelium and mesenchyme during development. Mutations that disrupt formation of either the correct number or shape of epithelial branches affect lung function. This, in turn, can lead t...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865378/ https://www.ncbi.nlm.nih.gov/pubmed/20223754 http://dx.doi.org/10.1093/hmg/ddq104 |