The analysis of PIK3CA mutations in gastric carcinoma and metanalysis of literature suggest that exon-selectivity is a signature of cancer type

BACKGROUND: PIK3CA is one of the genes most frequently mutated in human cancers and it is a potential target for personalized therapy. The aim of this study was to assess the frequency and type of PIK3CA mutations in gastric carcinoma and compare them with their clinical pathological correlates. MET...

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Detalles Bibliográficos
Autores principales: Barbi, Stefano, Cataldo, Ivana, De Manzoni, Giovanni, Bersani, Samantha, Lamba, Simona, Mattuzzi, Silvia, Bardelli, Alberto, Scarpa, Aldo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865450/
https://www.ncbi.nlm.nih.gov/pubmed/20398348
http://dx.doi.org/10.1186/1756-9966-29-32

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