N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor

BACKGROUND: Microglia provide continuous immune surveillance of the CNS and upon activation rapidly change phenotype to express receptors that respond to chemoattractants during CNS damage or infection. These activated microglia undergo directed migration towards affected tissue. Importantly, the mo...

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Detalles Bibliográficos
Autores principales: McHugh, Douglas, Hu, Sherry SJ, Rimmerman, Neta, Juknat, Ana, Vogel, Zvi, Walker, J Michael, Bradshaw, Heather B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865488/
https://www.ncbi.nlm.nih.gov/pubmed/20346144
http://dx.doi.org/10.1186/1471-2202-11-44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865488/
https://www.ncbi.nlm.nih.gov/pubmed/20346144
http://dx.doi.org/10.1186/1471-2202-11-44

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