Modeling Reveals Bistability and Low-Pass Filtering in the Network Module Determining Blood Stem Cell Fate

Combinatorial regulation of gene expression is ubiquitous in eukaryotes with multiple inputs converging on regulatory control elements. The dynamic properties of these elements determine the functionality of genetic networks regulating differentiation and development. Here we propose a method to qua...

Descripción completa

Detalles Bibliográficos
Autores principales: Narula, Jatin, Smith, Aileen M., Gottgens, Berthold, Igoshin, Oleg A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865510/
https://www.ncbi.nlm.nih.gov/pubmed/20463872
http://dx.doi.org/10.1371/journal.pcbi.1000771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865510/
https://www.ncbi.nlm.nih.gov/pubmed/20463872
http://dx.doi.org/10.1371/journal.pcbi.1000771

Ejemplares similares