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Host-Detrimental Role of Esx-1-Mediated Inflammasome Activation in Mycobacterial Infection

The Esx-1 (type VII) secretion system is a major virulence determinant of pathogenic mycobacteria, including Mycobacterium marinum. However, the molecular events and host-pathogen interactions underlying Esx-1-mediated virulence in vivo remain unclear. Here we address this problem in a non-lethal mo...

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Detalles Bibliográficos
Autores principales:	Carlsson, Fredric, Kim, Janice, Dumitru, Calin, Barck, Kai H., Carano, Richard A. D., Sun, Mei, Diehl, Lauri, Brown, Eric J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865529/ https://www.ncbi.nlm.nih.gov/pubmed/20463815 http://dx.doi.org/10.1371/journal.ppat.1000895

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