Infidelity of SARS-CoV Nsp14-Exonuclease Mutant Virus Replication Is Revealed by Complete Genome Sequencing

Most RNA viruses lack the mechanisms to recognize and correct mutations that arise during genome replication, resulting in quasispecies diversity that is required for pathogenesis and adaptation. However, it is not known how viruses encoding large viral RNA genomes such as the Coronaviridae (26 to 3...

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Detalles Bibliográficos
Autores principales: Eckerle, Lance D., Becker, Michelle M., Halpin, Rebecca A., Li, Kelvin, Venter, Eli, Lu, Xiaotao, Scherbakova, Sana, Graham, Rachel L., Baric, Ralph S., Stockwell, Timothy B., Spiro, David J., Denison, Mark R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865531/
https://www.ncbi.nlm.nih.gov/pubmed/20463816
http://dx.doi.org/10.1371/journal.ppat.1000896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865531/
https://www.ncbi.nlm.nih.gov/pubmed/20463816
http://dx.doi.org/10.1371/journal.ppat.1000896

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