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An RNA polymerase II- and AGO4-associated protein acts in RNA-directed DNA methylation

DNA methylation is an important epigenetic mark in many eukaryotes1-5. In plants, 24-nt small interfering RNAs (siRNAs) bound to the effector protein, Argonaute 4 (AGO4) can direct de novo DNA methylation by the methyltransferase DRM22,4-6. Here we report a new regulator of RNA-directed DNA methylat...

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Detalles Bibliográficos
Autores principales: Gao, Zhihuan, Liu, Hai-Liang, Daxinger, Lucia, Pontes, Olga, He, Xinjian, Qian, Weiqiang, Lin, Huixin, Xie, Mingtang, Lorkovic, Zdravko J., Zhang, Shoudong, Miki, Daisuke, Zhan, Xianqiang, Pontier, Dominique, Lagrange, Thierry, Jin, Hailing, Matzke, Antonius J., Matzke, Marjori, Pikaard, Craig S., Zhu, Jian-Kang
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865564/
https://www.ncbi.nlm.nih.gov/pubmed/20410883
http://dx.doi.org/10.1038/nature09025