Cancer risk in patients hospitalised for Graves’ disease: a population-based cohort study in Sweden

BACKGROUND: The possibility of an association of Graves’ disease (GD) with subsequent cancers raised by certain studies. METHODS: Using a database on 18 156 hospitalised GD patients, subsequent cancers were ascertained. RESULTS: Increased risks of thyroid and parathyroid tumours were limited to the...

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Detalles Bibliográficos
Autores principales: Shu, X, Ji, J, Li, X, Sundquist, J, Sundquist, K, Hemminki, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865750/
https://www.ncbi.nlm.nih.gov/pubmed/20354521
http://dx.doi.org/10.1038/sj.bjc.6605624
Descripción
Sumario:BACKGROUND: The possibility of an association of Graves’ disease (GD) with subsequent cancers raised by certain studies. METHODS: Using a database on 18 156 hospitalised GD patients, subsequent cancers were ascertained. RESULTS: Increased risks of thyroid and parathyroid tumours were limited to the early follow-up period, which is probably a surveillance bias. Cancer sites with observed excess included the mouth and breast, in contrast to decreased risks of colon cancer, melanoma and non-Hodgkin's lymphoma. CONCLUSION: Increased subsequent cancers in GD patients appeared to be balanced by decreased risks at other sites; chance cannot be excluded.

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