Cancer risk in patients hospitalised for Graves’ disease: a population-based cohort study in Sweden

BACKGROUND: The possibility of an association of Graves’ disease (GD) with subsequent cancers raised by certain studies. METHODS: Using a database on 18 156 hospitalised GD patients, subsequent cancers were ascertained. RESULTS: Increased risks of thyroid and parathyroid tumours were limited to the...

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Autores principales: Shu, X, Ji, J, Li, X, Sundquist, J, Sundquist, K, Hemminki, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865750/
https://www.ncbi.nlm.nih.gov/pubmed/20354521
http://dx.doi.org/10.1038/sj.bjc.6605624
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author Shu, X
Ji, J
Li, X
Sundquist, J
Sundquist, K
Hemminki, K
author_facet Shu, X
Ji, J
Li, X
Sundquist, J
Sundquist, K
Hemminki, K
author_sort Shu, X
collection PubMed
description BACKGROUND: The possibility of an association of Graves’ disease (GD) with subsequent cancers raised by certain studies. METHODS: Using a database on 18 156 hospitalised GD patients, subsequent cancers were ascertained. RESULTS: Increased risks of thyroid and parathyroid tumours were limited to the early follow-up period, which is probably a surveillance bias. Cancer sites with observed excess included the mouth and breast, in contrast to decreased risks of colon cancer, melanoma and non-Hodgkin's lymphoma. CONCLUSION: Increased subsequent cancers in GD patients appeared to be balanced by decreased risks at other sites; chance cannot be excluded.
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spelling pubmed-28657502011-04-27 Cancer risk in patients hospitalised for Graves’ disease: a population-based cohort study in Sweden Shu, X Ji, J Li, X Sundquist, J Sundquist, K Hemminki, K Br J Cancer Short Communication BACKGROUND: The possibility of an association of Graves’ disease (GD) with subsequent cancers raised by certain studies. METHODS: Using a database on 18 156 hospitalised GD patients, subsequent cancers were ascertained. RESULTS: Increased risks of thyroid and parathyroid tumours were limited to the early follow-up period, which is probably a surveillance bias. Cancer sites with observed excess included the mouth and breast, in contrast to decreased risks of colon cancer, melanoma and non-Hodgkin's lymphoma. CONCLUSION: Increased subsequent cancers in GD patients appeared to be balanced by decreased risks at other sites; chance cannot be excluded. Nature Publishing Group 2010-04-27 2010-03-30 /pmc/articles/PMC2865750/ /pubmed/20354521 http://dx.doi.org/10.1038/sj.bjc.6605624 Text en Copyright © 2010 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Short Communication
Shu, X
Ji, J
Li, X
Sundquist, J
Sundquist, K
Hemminki, K
Cancer risk in patients hospitalised for Graves’ disease: a population-based cohort study in Sweden
title Cancer risk in patients hospitalised for Graves’ disease: a population-based cohort study in Sweden
title_full Cancer risk in patients hospitalised for Graves’ disease: a population-based cohort study in Sweden
title_fullStr Cancer risk in patients hospitalised for Graves’ disease: a population-based cohort study in Sweden
title_full_unstemmed Cancer risk in patients hospitalised for Graves’ disease: a population-based cohort study in Sweden
title_short Cancer risk in patients hospitalised for Graves’ disease: a population-based cohort study in Sweden
title_sort cancer risk in patients hospitalised for graves’ disease: a population-based cohort study in sweden
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865750/
https://www.ncbi.nlm.nih.gov/pubmed/20354521
http://dx.doi.org/10.1038/sj.bjc.6605624
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