Synthesis, Antiinflammatory and HIV-1 Integrase Inhibitory Activities of 1,2-Bis[5-thiazolyl]ethane-1,2-dione Derivatives

Based on principles of pharmacophore delineation and drug designing, compounds containing diketofunctionallity namely 1,2-bis[5-thiazolyl]ethane-1,2-diones were designed and synthesized as antiinflammatory agents. The compounds were evaluated in carrageenan-induced rat-paw edema method. G-3, G-6, G-...

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Detalles Bibliográficos
Autores principales: Franklin, P. X., Yerande, S., Thakar, H. M., Inamdar, G. S., Giri, R. S., Padh, H., Sudarsanam, V., Vasu, Kamala K.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865783/
https://www.ncbi.nlm.nih.gov/pubmed/20490291
http://dx.doi.org/10.4103/0250-474X.56021

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