Characterization of Gelatin-Sodium Alginate Complex Coacervation System

A gelatin and sodium alginate complex coacervation system was studied and an effect of pH and colloid mixing ratios on coacervation was investigated. A colloid mixing ratio at which optimum coacervation occurred varied with the coacervation pH. Viscometric, turbidity and coacervate dry yield investi...

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Autores principales: Shinde, Ujwala A., Nagarsenker, Mangal S.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865794/
https://www.ncbi.nlm.nih.gov/pubmed/20490302
http://dx.doi.org/10.4103/0250-474X.56033
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author Shinde, Ujwala A.
Nagarsenker, Mangal S.
author_facet Shinde, Ujwala A.
Nagarsenker, Mangal S.
author_sort Shinde, Ujwala A.
collection PubMed
description A gelatin and sodium alginate complex coacervation system was studied and an effect of pH and colloid mixing ratios on coacervation was investigated. A colloid mixing ratio at which optimum coacervation occurred varied with the coacervation pH. Viscometric, turbidity and coacervate dry yield investigations were used to investigate optimum conditions for complex coacervation. Optimum coacervation occurred at pH 3.5 at a gelatin sodium alginate ratio 4:1. Coacervate and equilibrium fluid was analyzed for gelatin and sodium alginate contents and yields calculated on the basis of chemical analysis showed that optimum coacervation occurred at 25% sodium alginate fraction at pH 3.5.
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spelling pubmed-28657942010-05-20 Characterization of Gelatin-Sodium Alginate Complex Coacervation System Shinde, Ujwala A. Nagarsenker, Mangal S. Indian J Pharm Sci Short Communication A gelatin and sodium alginate complex coacervation system was studied and an effect of pH and colloid mixing ratios on coacervation was investigated. A colloid mixing ratio at which optimum coacervation occurred varied with the coacervation pH. Viscometric, turbidity and coacervate dry yield investigations were used to investigate optimum conditions for complex coacervation. Optimum coacervation occurred at pH 3.5 at a gelatin sodium alginate ratio 4:1. Coacervate and equilibrium fluid was analyzed for gelatin and sodium alginate contents and yields calculated on the basis of chemical analysis showed that optimum coacervation occurred at 25% sodium alginate fraction at pH 3.5. Medknow Publications 2009 /pmc/articles/PMC2865794/ /pubmed/20490302 http://dx.doi.org/10.4103/0250-474X.56033 Text en © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Shinde, Ujwala A.
Nagarsenker, Mangal S.
Characterization of Gelatin-Sodium Alginate Complex Coacervation System
title Characterization of Gelatin-Sodium Alginate Complex Coacervation System
title_full Characterization of Gelatin-Sodium Alginate Complex Coacervation System
title_fullStr Characterization of Gelatin-Sodium Alginate Complex Coacervation System
title_full_unstemmed Characterization of Gelatin-Sodium Alginate Complex Coacervation System
title_short Characterization of Gelatin-Sodium Alginate Complex Coacervation System
title_sort characterization of gelatin-sodium alginate complex coacervation system
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865794/
https://www.ncbi.nlm.nih.gov/pubmed/20490302
http://dx.doi.org/10.4103/0250-474X.56033
work_keys_str_mv AT shindeujwalaa characterizationofgelatinsodiumalginatecomplexcoacervationsystem
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