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Co-Crystals: A Novel Approach to Modify Physicochemical Properties of Active Pharmaceutical Ingredients
Crystal form can be crucial to the performance of a dosage form. This is especially true for compounds that have intrinsic barriers to drug delivery, such as low aqueous solubility, slow dissolution in gastrointestinal media, low permeability and first-pass metabolism. The nature of the physical for...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865806/ https://www.ncbi.nlm.nih.gov/pubmed/20502540 http://dx.doi.org/10.4103/0250-474X.57283 |