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Co-Crystals: A Novel Approach to Modify Physicochemical Properties of Active Pharmaceutical Ingredients

Crystal form can be crucial to the performance of a dosage form. This is especially true for compounds that have intrinsic barriers to drug delivery, such as low aqueous solubility, slow dissolution in gastrointestinal media, low permeability and first-pass metabolism. The nature of the physical for...

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Detalles Bibliográficos
Autores principales: Yadav, A. V., Shete, A. S., Dabke, A. P., Kulkarni, P. V., Sakhare, S. S.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865806/
https://www.ncbi.nlm.nih.gov/pubmed/20502540
http://dx.doi.org/10.4103/0250-474X.57283