CNS Depressant Activity of Ethanol Extract of Sterculia guttata seeds in mice

Shade dried, powdered seeds of Sterculia guttata were extracted using a Soxhlet extractor with ethanol. Ethanol was removed under reduced pressure and dried to obtained crude extract. This extract was evaluated for its effect on behavioral changes, exploratory activity and barbiturate-sleeping time,...

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Detalles Bibliográficos
Autores principales: Katade, S. R., Misar, A. V., Mujumdar, A. M., Phalgune, U. D., Wakharkar, R. D., Deshpande, N. R.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865820/
https://www.ncbi.nlm.nih.gov/pubmed/20502554
http://dx.doi.org/10.4103/0250-474X.57297
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author Katade, S. R.
Misar, A. V.
Mujumdar, A. M.
Phalgune, U. D.
Wakharkar, R. D.
Deshpande, N. R.
author_facet Katade, S. R.
Misar, A. V.
Mujumdar, A. M.
Phalgune, U. D.
Wakharkar, R. D.
Deshpande, N. R.
author_sort Katade, S. R.
collection PubMed
description Shade dried, powdered seeds of Sterculia guttata were extracted using a Soxhlet extractor with ethanol. Ethanol was removed under reduced pressure and dried to obtained crude extract. This extract was evaluated for its effect on behavioral changes, exploratory activity and barbiturate-sleeping time, using appropriate standard methods in mice. The extract exhibited dose-dependent CNS depressant activity.
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spelling pubmed-28658202010-05-25 CNS Depressant Activity of Ethanol Extract of Sterculia guttata seeds in mice Katade, S. R. Misar, A. V. Mujumdar, A. M. Phalgune, U. D. Wakharkar, R. D. Deshpande, N. R. Indian J Pharm Sci Short Communication Shade dried, powdered seeds of Sterculia guttata were extracted using a Soxhlet extractor with ethanol. Ethanol was removed under reduced pressure and dried to obtained crude extract. This extract was evaluated for its effect on behavioral changes, exploratory activity and barbiturate-sleeping time, using appropriate standard methods in mice. The extract exhibited dose-dependent CNS depressant activity. Medknow Publications 2009 /pmc/articles/PMC2865820/ /pubmed/20502554 http://dx.doi.org/10.4103/0250-474X.57297 Text en © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Katade, S. R.
Misar, A. V.
Mujumdar, A. M.
Phalgune, U. D.
Wakharkar, R. D.
Deshpande, N. R.
CNS Depressant Activity of Ethanol Extract of Sterculia guttata seeds in mice
title CNS Depressant Activity of Ethanol Extract of Sterculia guttata seeds in mice
title_full CNS Depressant Activity of Ethanol Extract of Sterculia guttata seeds in mice
title_fullStr CNS Depressant Activity of Ethanol Extract of Sterculia guttata seeds in mice
title_full_unstemmed CNS Depressant Activity of Ethanol Extract of Sterculia guttata seeds in mice
title_short CNS Depressant Activity of Ethanol Extract of Sterculia guttata seeds in mice
title_sort cns depressant activity of ethanol extract of sterculia guttata seeds in mice
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865820/
https://www.ncbi.nlm.nih.gov/pubmed/20502554
http://dx.doi.org/10.4103/0250-474X.57297
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