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Calpain 4 Is Not Necessary for LFA-1-Mediated Function in CD4+ T Cells

BACKGROUND: T cell activation and immune synapse formation require the appropriate activation and clustering of the integrin, LFA-1. Previous work has reported that the calpain family of calcium-dependent proteases are important regulators of integrin activation and modulate T cell adhesion and migr...

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Detalles Bibliográficos
Autores principales:	Wernimont, Sarah A., Simonson, William T. N., Greer, Peter A., Seroogy, Christine M., Huttenlocher, Anna
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866319/ https://www.ncbi.nlm.nih.gov/pubmed/20479866 http://dx.doi.org/10.1371/journal.pone.0010513

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