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The Isoelectric Region of Proteins: A Systematic Analysis

BACKGROUND: Binding of proteins in ion exchange chromatography is dominated by electrostatic interactions and can be tuned by adjusting pH and ionic strength of the solvent. Therefore, the isoelectric region (IER), the pH region of almost zero charge near the pI, has been used to predict the binding...

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Detalles Bibliográficos
Autores principales: Widmann, Michael, Trodler, Peter, Pleiss, Jürgen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866324/
https://www.ncbi.nlm.nih.gov/pubmed/20479870
http://dx.doi.org/10.1371/journal.pone.0010546