Protective Effect of Ginger oil on Aspirin and Pylorus Ligation-Induced Gastric Ulcer model in Rats

The present investigation was performed in aspirin and pylorus ligation-induced ulcer model in Wistar rats, in which ability of ginger oil to provide gastric protection was studied at two different doses, 0.5 and 1 g/kg po. Gastric protection was evaluated by measuring the ulcer index, serum γ-GTP l...

Descripción completa

Detalles Bibliográficos
Autores principales: Khushtar, M., Kumar, V., Javed, K., Bhandari, Uma
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866350/
https://www.ncbi.nlm.nih.gov/pubmed/20502577
http://dx.doi.org/10.4103/0250-474X.58195
_version_ 1782180896275693568
author Khushtar, M.
Kumar, V.
Javed, K.
Bhandari, Uma
author_facet Khushtar, M.
Kumar, V.
Javed, K.
Bhandari, Uma
author_sort Khushtar, M.
collection PubMed
description The present investigation was performed in aspirin and pylorus ligation-induced ulcer model in Wistar rats, in which ability of ginger oil to provide gastric protection was studied at two different doses, 0.5 and 1 g/kg po. Gastric protection was evaluated by measuring the ulcer index, serum γ-GTP levels, total acidity of gastric juice and gastric wall mucus thickness. The results obtained in the present study indicated that ginger oil has a protective action against gastric ulcers induced by aspirin plus pylorus ligation in Wistar rats.
format Text
id pubmed-2866350
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher Medknow Publications
record_format MEDLINE/PubMed
spelling pubmed-28663502010-05-25 Protective Effect of Ginger oil on Aspirin and Pylorus Ligation-Induced Gastric Ulcer model in Rats Khushtar, M. Kumar, V. Javed, K. Bhandari, Uma Indian J Pharm Sci Short Communication The present investigation was performed in aspirin and pylorus ligation-induced ulcer model in Wistar rats, in which ability of ginger oil to provide gastric protection was studied at two different doses, 0.5 and 1 g/kg po. Gastric protection was evaluated by measuring the ulcer index, serum γ-GTP levels, total acidity of gastric juice and gastric wall mucus thickness. The results obtained in the present study indicated that ginger oil has a protective action against gastric ulcers induced by aspirin plus pylorus ligation in Wistar rats. Medknow Publications 2009 /pmc/articles/PMC2866350/ /pubmed/20502577 http://dx.doi.org/10.4103/0250-474X.58195 Text en © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Khushtar, M.
Kumar, V.
Javed, K.
Bhandari, Uma
Protective Effect of Ginger oil on Aspirin and Pylorus Ligation-Induced Gastric Ulcer model in Rats
title Protective Effect of Ginger oil on Aspirin and Pylorus Ligation-Induced Gastric Ulcer model in Rats
title_full Protective Effect of Ginger oil on Aspirin and Pylorus Ligation-Induced Gastric Ulcer model in Rats
title_fullStr Protective Effect of Ginger oil on Aspirin and Pylorus Ligation-Induced Gastric Ulcer model in Rats
title_full_unstemmed Protective Effect of Ginger oil on Aspirin and Pylorus Ligation-Induced Gastric Ulcer model in Rats
title_short Protective Effect of Ginger oil on Aspirin and Pylorus Ligation-Induced Gastric Ulcer model in Rats
title_sort protective effect of ginger oil on aspirin and pylorus ligation-induced gastric ulcer model in rats
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866350/
https://www.ncbi.nlm.nih.gov/pubmed/20502577
http://dx.doi.org/10.4103/0250-474X.58195
work_keys_str_mv AT khushtarm protectiveeffectofgingeroilonaspirinandpylorusligationinducedgastriculcermodelinrats
AT kumarv protectiveeffectofgingeroilonaspirinandpylorusligationinducedgastriculcermodelinrats
AT javedk protectiveeffectofgingeroilonaspirinandpylorusligationinducedgastriculcermodelinrats
AT bhandariuma protectiveeffectofgingeroilonaspirinandpylorusligationinducedgastriculcermodelinrats

Ejemplares similares