General Anesthetic Actions on GABA(A) Receptors

General anesthetic drugs interact with many receptors in the nervous system, but only a handful of these interactions are critical for producing anesthesia. Over the last 20 years, neuropharmacologists have revealed that one of the most important target sites for general anesthetics is the GABA(A) r...

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Detalles Bibliográficos
Autores principales: Garcia, Paul S, Kolesky, Scott E, Jenkins, Andrew
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866459/
https://www.ncbi.nlm.nih.gov/pubmed/20808541
http://dx.doi.org/10.2174/157015910790909502
Descripción
Sumario:General anesthetic drugs interact with many receptors in the nervous system, but only a handful of these interactions are critical for producing anesthesia. Over the last 20 years, neuropharmacologists have revealed that one of the most important target sites for general anesthetics is the GABA(A) receptor. In this review we will discuss what is known about anesthetic – GABA(A) receptor interactions.

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