General Anesthetic Actions on GABA(A) Receptors

General anesthetic drugs interact with many receptors in the nervous system, but only a handful of these interactions are critical for producing anesthesia. Over the last 20 years, neuropharmacologists have revealed that one of the most important target sites for general anesthetics is the GABA(A) r...

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Detalles Bibliográficos
Autores principales: Garcia, Paul S, Kolesky, Scott E, Jenkins, Andrew
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866459/
https://www.ncbi.nlm.nih.gov/pubmed/20808541
http://dx.doi.org/10.2174/157015910790909502
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author Garcia, Paul S
Kolesky, Scott E
Jenkins, Andrew
author_facet Garcia, Paul S
Kolesky, Scott E
Jenkins, Andrew
author_sort Garcia, Paul S
collection PubMed
description General anesthetic drugs interact with many receptors in the nervous system, but only a handful of these interactions are critical for producing anesthesia. Over the last 20 years, neuropharmacologists have revealed that one of the most important target sites for general anesthetics is the GABA(A) receptor. In this review we will discuss what is known about anesthetic – GABA(A) receptor interactions.
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spelling pubmed-28664592010-09-01 General Anesthetic Actions on GABA(A) Receptors Garcia, Paul S Kolesky, Scott E Jenkins, Andrew Curr Neuropharmacol Article General anesthetic drugs interact with many receptors in the nervous system, but only a handful of these interactions are critical for producing anesthesia. Over the last 20 years, neuropharmacologists have revealed that one of the most important target sites for general anesthetics is the GABA(A) receptor. In this review we will discuss what is known about anesthetic – GABA(A) receptor interactions. Bentham Science Publishers Ltd. 2010-03 /pmc/articles/PMC2866459/ /pubmed/20808541 http://dx.doi.org/10.2174/157015910790909502 Text en ©2010 Bentham Science Publishers Ltd. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Garcia, Paul S
Kolesky, Scott E
Jenkins, Andrew
General Anesthetic Actions on GABA(A) Receptors
title General Anesthetic Actions on GABA(A) Receptors
title_full General Anesthetic Actions on GABA(A) Receptors
title_fullStr General Anesthetic Actions on GABA(A) Receptors
title_full_unstemmed General Anesthetic Actions on GABA(A) Receptors
title_short General Anesthetic Actions on GABA(A) Receptors
title_sort general anesthetic actions on gaba(a) receptors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866459/
https://www.ncbi.nlm.nih.gov/pubmed/20808541
http://dx.doi.org/10.2174/157015910790909502
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