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Global Chromatin Architecture Reflects Pluripotency and Lineage Commitment in the Early Mouse Embryo
An open chromatin architecture devoid of compact chromatin is thought to be associated with pluripotency in embryonic stem cells. Establishing this distinct epigenetic state may also be required for somatic cell reprogramming. However, there has been little direct examination of global structural do...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866533/ https://www.ncbi.nlm.nih.gov/pubmed/20479880 http://dx.doi.org/10.1371/journal.pone.0010531 |