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Inhibition of Hypoxia-Inducible Factor-1α (HIF-1α) Protein Synthesis by DNA Damage Inducing Agents

Hypoxia-inducible factor (HIF) is a heterodimeric transcription factor that is composed of a hypoxia-inducible α subunit (HIF-1α and HIF-2α) and a constitutively expressed β subunit (HIF-1β). HIF mediates the adaptation of cells and tissues to low oxygen concentrations. It also plays an important ro...

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Detalles Bibliográficos
Autores principales:	Lou, Jessica Jie Wei, Chua, Yee Liu, Chew, Eng Hui, Gao, Jie, Bushell, Martin, Hagen, Thilo
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866540/ https://www.ncbi.nlm.nih.gov/pubmed/20479887 http://dx.doi.org/10.1371/journal.pone.0010522

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