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Quantitative Metabolomics by (1)H-NMR and LC-MS/MS Confirms Altered Metabolic Pathways in Diabetes
Insulin is as a major postprandial hormone with profound effects on carbohydrate, fat, and protein metabolism. In the absence of exogenous insulin, patients with type 1 diabetes exhibit a variety of metabolic abnormalities including hyperglycemia, glycosurea, accelerated ketogenesis, and muscle wast...
Autores principales: | Lanza, Ian R., Zhang, Shucha, Ward, Lawrence E., Karakelides, Helen, Raftery, Daniel, Nair, K. Sreekumaran |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866659/ https://www.ncbi.nlm.nih.gov/pubmed/20479934 http://dx.doi.org/10.1371/journal.pone.0010538 |
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