What Role for Biologically Based Dose–Response Models in Estimating Low-Dose Risk?

BACKGROUND: Biologically based dose–response (BBDR) models can incorporate data on biological processes at the cellular and molecular level to link external exposure to an adverse effect. OBJECTIVES: Our goal was to examine the utility of BBDR models in estimating low-dose risk. METHODS: We reviewed...

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Detalles Bibliográficos
Autores principales: Crump, Kenny S., Chen, Chao, Chiu, Weihsueh A., Louis, Thomas A., Portier, Christopher J., Subramaniam, Ravi P., White, Paul D.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2010
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866670/
https://www.ncbi.nlm.nih.gov/pubmed/20056564
http://dx.doi.org/10.1289/ehp.0901249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866670/
https://www.ncbi.nlm.nih.gov/pubmed/20056564
http://dx.doi.org/10.1289/ehp.0901249

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