Hormone Activity of Hydroxylated Polybrominated Diphenyl Ethers on Human Thyroid Receptor-β: In Vitro and In Silico Investigations

BACKGROUND: Hydroxylated polybrominated diphenyl ethers (HO-PBDEs) may disrupt thyroid hormone status because of their structural similarity to thyroid hormone. However, the molecular mechanisms of interactions with thyroid hormone receptors (TRs) are not fully understood. OBJECTIVES: We investigate...

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Detalles Bibliográficos
Autores principales: Li, Fei, Xie, Qing, Li, Xuehua, Li, Na, Chi, Ping, Chen, Jingwen, Wang, Zijian, Hao, Ce
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866673/
https://www.ncbi.nlm.nih.gov/pubmed/20439171
http://dx.doi.org/10.1289/ehp.0901457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866673/
https://www.ncbi.nlm.nih.gov/pubmed/20439171
http://dx.doi.org/10.1289/ehp.0901457

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