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Mcl-1 promotes survival of thymocytes by inhibition of Bak in a pathway separate from Bcl-2
The anti-apoptotic proteins Mcl-1 and Bcl-2 have been shown to be critical in T cell development and homeostasis, but the precise mechanism by which these proteins function in T cells and other cells of the body is unclear. Potential mechanisms have allowed both for overlapping and unique roles for...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866813/ https://www.ncbi.nlm.nih.gov/pubmed/20057504 http://dx.doi.org/10.1038/cdd.2009.201 |