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GM-CSF–dependent, CD103(+) dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization

Dendritic cells (DCs) play an important role in CD4(+) T helper (Th) cell differentiation and in the initiation of both protective and pathogenic immunity. Granulocyte/macrophage colony-stimulating factor (GM-CSF) is a DC growth factor critical for the induction of experimental autoimmune encephalom...

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Detalles Bibliográficos
Autores principales: King, Irah L., Kroenke, Mark A., Segal, Benjamin M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867280/
https://www.ncbi.nlm.nih.gov/pubmed/20421390
http://dx.doi.org/10.1084/jem.20091844