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Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation

The roles of autoimmune regulator (Aire)–expressing medullary thymic epithelial cells (mTECs) in the organization of the thymic microenvironment for establishing self-tolerance are enigmatic. We sought to monitor the production and maintenance of Aire-expressing mTECs by a fate-mapping strategy in w...

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Detalles Bibliográficos
Autores principales:	Nishikawa, Yumiko, Hirota, Fumiko, Yano, Masashi, Kitajima, Hiroyuki, Miyazaki, Jun-ichi, Kawamoto, Hiroshi, Mouri, Yasuhiro, Matsumoto, Mitsuru
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867289/ https://www.ncbi.nlm.nih.gov/pubmed/20404099 http://dx.doi.org/10.1084/jem.20092144

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