Peripheral T cell lymphoma: new model + new insight

The nonreceptor tyrosine kinase SYK has recently received a good deal of attention as a critical oncogene in various hematologic malignancies. A newly developed model of peripheral T cell lymphoma (PTCL) using the ITK-SYK fusion gene should serve as a powerful tool to dissect the signaling cascades...

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Detalles Bibliográficos
Autor principal: Mulloy, James C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867292/
https://www.ncbi.nlm.nih.gov/pubmed/20439538
http://dx.doi.org/10.1084/jem.20100608
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author Mulloy, James C.
author_facet Mulloy, James C.
author_sort Mulloy, James C.
collection PubMed
description The nonreceptor tyrosine kinase SYK has recently received a good deal of attention as a critical oncogene in various hematologic malignancies. A newly developed model of peripheral T cell lymphoma (PTCL) using the ITK-SYK fusion gene should serve as a powerful tool to dissect the signaling cascades important for SYK-associated malignancy in the context of t(5;9) PTCL.
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spelling pubmed-28672922010-11-10 Peripheral T cell lymphoma: new model + new insight Mulloy, James C. J Exp Med Commentary The nonreceptor tyrosine kinase SYK has recently received a good deal of attention as a critical oncogene in various hematologic malignancies. A newly developed model of peripheral T cell lymphoma (PTCL) using the ITK-SYK fusion gene should serve as a powerful tool to dissect the signaling cascades important for SYK-associated malignancy in the context of t(5;9) PTCL. The Rockefeller University Press 2010-05-10 /pmc/articles/PMC2867292/ /pubmed/20439538 http://dx.doi.org/10.1084/jem.20100608 Text en © 2010 Mulloy This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Commentary
Mulloy, James C.
Peripheral T cell lymphoma: new model + new insight
title Peripheral T cell lymphoma: new model + new insight
title_full Peripheral T cell lymphoma: new model + new insight
title_fullStr Peripheral T cell lymphoma: new model + new insight
title_full_unstemmed Peripheral T cell lymphoma: new model + new insight
title_short Peripheral T cell lymphoma: new model + new insight
title_sort peripheral t cell lymphoma: new model + new insight
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867292/
https://www.ncbi.nlm.nih.gov/pubmed/20439538
http://dx.doi.org/10.1084/jem.20100608
work_keys_str_mv AT mulloyjamesc peripheraltcelllymphomanewmodelnewinsight

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