N-cadherin: stabilizing synapses

Spines are sites of excitatory synapse formation in central neurons. Alterations in spine structure and function are widely believed to actively contribute to the cellular mechanisms of learning and memory. In this issue, Mendez et al. (2010. J. Cell Biol. doi:10.1083/jcb.201003007) demonstrate a pi...

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Detalles Bibliográficos
Autor principal: Arikkath, Jyothi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867313/
https://www.ncbi.nlm.nih.gov/pubmed/20439992
http://dx.doi.org/10.1083/jcb.201004022
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author Arikkath, Jyothi
author_facet Arikkath, Jyothi
author_sort Arikkath, Jyothi
collection PubMed
description Spines are sites of excitatory synapse formation in central neurons. Alterations in spine structure and function are widely believed to actively contribute to the cellular mechanisms of learning and memory. In this issue, Mendez et al. (2010. J. Cell Biol. doi:10.1083/jcb.201003007) demonstrate a pivotal role for the cell adhesion molecule N-cadherin in activity-mediated spine stabilization, offering a new mechanism for how spine dynamics and stability are regulated by activity in central neurons.
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spelling pubmed-28673132010-11-03 N-cadherin: stabilizing synapses Arikkath, Jyothi J Cell Biol Reviews Spines are sites of excitatory synapse formation in central neurons. Alterations in spine structure and function are widely believed to actively contribute to the cellular mechanisms of learning and memory. In this issue, Mendez et al. (2010. J. Cell Biol. doi:10.1083/jcb.201003007) demonstrate a pivotal role for the cell adhesion molecule N-cadherin in activity-mediated spine stabilization, offering a new mechanism for how spine dynamics and stability are regulated by activity in central neurons. The Rockefeller University Press 2010-05-03 /pmc/articles/PMC2867313/ /pubmed/20439992 http://dx.doi.org/10.1083/jcb.201004022 Text en © 2010 Arikkath This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Arikkath, Jyothi
N-cadherin: stabilizing synapses
title N-cadherin: stabilizing synapses
title_full N-cadherin: stabilizing synapses
title_fullStr N-cadherin: stabilizing synapses
title_full_unstemmed N-cadherin: stabilizing synapses
title_short N-cadherin: stabilizing synapses
title_sort n-cadherin: stabilizing synapses
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867313/
https://www.ncbi.nlm.nih.gov/pubmed/20439992
http://dx.doi.org/10.1083/jcb.201004022
work_keys_str_mv AT arikkathjyothi ncadherinstabilizingsynapses

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