The transcription factor RBP-J-mediated signaling is essential for dendritic cells to evoke efficient anti-tumor immune responses in mice

BACKGROUND: Dendritic cells (DCs) are professional antigen presenting cells that initiate specific immune responses against tumor cells. Transcription factor RBP-J-mediated Notch signaling regulates DC genesis, but whether this pathway regulates DC function in anti-tumor immunity remains unclear. In...

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Detalles Bibliográficos
Autores principales: Feng, Fan, Wang, Yao-Chun, Hu, Xing-Bin, Liu, Xiao-Wei, Ji, Gang, Chen, Yun-Ru, Wang, Lin, He, Fei, Dou, Guo-Rui, Liang, Liang, Zhang, Hong-Wei, Han, Hua
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867822/
https://www.ncbi.nlm.nih.gov/pubmed/20420708
http://dx.doi.org/10.1186/1476-4598-9-90

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