Interdomain Interactions Control Ca(2+)-Dependent Potentiation in the Cation Channel TRPV4

Several Ca(2+)-permeable channels, including the non-selective cation channel TRPV4, are subject to Ca(2+)-dependent facilitation. Although it has been clearly demonstrated in functional experiments that calmodulin (CaM) binding to intracellular domains of TRP channels is involved in this process, t...

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Detalles Bibliográficos
Autores principales: Strotmann, Rainer, Semtner, Marcus, Kepura, Frauke, Plant, Tim D., Schöneberg, Torsten
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867956/
https://www.ncbi.nlm.nih.gov/pubmed/20485495
http://dx.doi.org/10.1371/journal.pone.0010580

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