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Synthesis, Solution, and Structural Characterization of Tetrahydrofuranyl-2,2-Bisphosphonic Acid Disodium Salt

Bisphosphonates are biologically relevant therapeutics for bone disorders and cancer. Reaction of γ-chlorobutyric acid, phosphorus acid, and phosphorus trichloride without the use of solvent gave the tetrahydrofuranyl-2,2-bisphosphonate sodium salt (Na(2)H(2)L). The Na(2)H(2)L was isolated, characte...

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Detalles Bibliográficos
Autores principales:	Maltezou, Elena, Stylianou, Marios, Roy, Sudeshna, Drouza, Chryssoula, Keramidas, Anastasios D.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868181/ https://www.ncbi.nlm.nih.gov/pubmed/20467558 http://dx.doi.org/10.1155/2010/563875

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