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Rhabdoid Tumor: Gene Expression Clues to Pathogenesis and Potential Therapeutic Targets

Rhabdoid tumors (RT) are aggressive tumors characterized by genetic loss of SMARCB1 (SNF5, INI-1), a component of the SWI/SNF chromatin remodeling complex. No effective treatment is currently available. This study seeks to shed light on the SMARCB1-mediated pathogenesis of RT and to discover potenti...

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Detalles Bibliográficos
Autores principales:	Gadd, Samantha, Sredni, Simone Treiger, Huang, Chiang-Ching, Perlman, Elizabeth J.
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868345/ https://www.ncbi.nlm.nih.gov/pubmed/20212451 http://dx.doi.org/10.1038/labinvest.2010.66

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