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Separating speed and ability to displace roadblocks during DNA translocation by FtsK

FtsK translocates dsDNA directionally at >5 kb/s, even under strong forces. In vivo, the action of FtsK at the bacterial division septum is required to complete the final stages of chromosome unlinking and segregation. Despite the availability of translocase structures, the mechanism by which ATP...

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Detalles Bibliográficos
Autores principales: Crozat, Estelle, Meglio, Adrien, Allemand, Jean-François, Chivers, Claire E, Howarth, Mark, Vénien-Bryan, Catherine, Grainge, Ian, Sherratt, David J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868570/
https://www.ncbi.nlm.nih.gov/pubmed/20379135
http://dx.doi.org/10.1038/emboj.2010.29