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VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts
The vascular endothelial growth factors VEGFA and VEGFC are crucial regulators of vascular development. They exert their effects by dimerization and activation of the cognate receptors VEGFR2 and VEGFR3. Here, we have used in situ proximity ligation to detect receptor complexes in intact endothelial...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868571/ https://www.ncbi.nlm.nih.gov/pubmed/20224550 http://dx.doi.org/10.1038/emboj.2010.30 |