Cargando…

VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

The vascular endothelial growth factors VEGFA and VEGFC are crucial regulators of vascular development. They exert their effects by dimerization and activation of the cognate receptors VEGFR2 and VEGFR3. Here, we have used in situ proximity ligation to detect receptor complexes in intact endothelial...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nilsson, Ingrid, Bahram, Fuad, Li, Xiujuan, Gualandi, Laura, Koch, Sina, Jarvius, Malin, Söderberg, Ola, Anisimov, Andrey, Kholová, Ivana, Pytowski, Bronislaw, Baldwin, Megan, Ylä-Herttuala, Seppo, Alitalo, Kari, Kreuger, Johan, Claesson-Welsh, Lena
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868571/ https://www.ncbi.nlm.nih.gov/pubmed/20224550 http://dx.doi.org/10.1038/emboj.2010.30

Ejemplares similares

Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting
por: Wirzenius, Maria, et al.
Publicado: (2007)

Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation
por: Huggenberger, Reto, et al.
Publicado: (2010)

Short and Long-Term Effects of hVEGF-A(165) in Cre-Activated Transgenic Mice
por: Leppänen, Pia, et al.
Publicado: (2006)

Comparison of Automated and Traditional Western Blotting Methods
por: Sormunen, Aino, et al.
Publicado: (2023)

SproutAngio: an open-source bioimage informatics tool for quantitative analysis of sprouting angiogenesis and lumen space
por: Beter, M., et al.
Publicado: (2023)

Viral-Vector-Delivered Anti-Angiogenic Therapies to the Eye
por: Koponen, Sanna, et al.
Publicado: (2021)

Specific Inhibition of SRC Kinase Impairs Malignant Glioma Growth In Vitro and In Vivo
por: Stedt, Hanna, et al.
Publicado: (2012)

Gene Therapy Used in Cancer Treatment
por: Wirth, Thomas, et al.
Publicado: (2014)

Therapeutic Potential of VEGF-B in Coronary Heart Disease and Heart Failure: Dream or Vision?
por: Mallick, Rahul, et al.
Publicado: (2022)

Lymphatic insufficiency leads to distinct myocardial infarct content assessed by magnetic resonance T(RAFFn), T(1ρ) and T(2) relaxation times
por: Ylä-Herttuala, Elias, et al.
Publicado: (2023)

EphrinB2/EphB4 signaling regulates non‐sprouting angiogenesis by VEGF
por: Groppa, Elena, et al.
Publicado: (2018)

Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction
por: Vuorio, Taina, et al.
Publicado: (2018)

Left ventricular dysfunction with reduced functional cardiac reserve in diabetic and non-diabetic LDL-receptor deficient apolipoprotein B100-only mice
por: Heinonen, Suvi E, et al.
Publicado: (2011)

Low-grade inflammation and the phenotypic expression of myocardial fibrosis in hypertrophic cardiomyopathy
por: Kuusisto, Johanna, et al.
Publicado: (2012)

Promoting blood vessel growth in ischemic diseases: challenges in translating preclinical potential into clinical success
por: Dragneva, Galina, et al.
Publicado: (2013)

Dotted collar placed around carotid artery induces asymmetric neointimal lesion formation in rabbits without intravascular manipulations
por: Kivelä, Antti, et al.
Publicado: (2012)

Characterization of a new IN-I-PpoI fusion protein and a homology-arm containing transgene cassette that improve transgene expression persistence and 28S rRNA gene-targeted insertion of lentiviral vectors
por: Nousiainen, Alisa, et al.
Publicado: (2023)

Lymphangiogenic Gene Therapy With Minimal Blood Vascular Side Effects
por: Saaristo, Anne, et al.
Publicado: (2002)

Improved endothelialization of small-diameter ePTFE vascular grafts through growth factor therapy
por: Hytönen, Jarkko P, et al.
Publicado: (2019)

Vascular Endothelial Growth Factor-B Induces a Distinct Electrophysiological Phenotype in Mouse Heart
por: Naumenko, Nikolay, et al.
Publicado: (2017)

A New Gene Therapy Approach for Cardiovascular Disease by Non-coding RNAs Acting in the Nucleus
por: Husso, Tiia, et al.
Publicado: (2014)

Nucleic Acid–Based Therapies for Atherosclerosis
por: Mäkinen, Petri, et al.
Publicado: (2020)

Novel RNAi-Based Therapies for Atherosclerosis
por: Ruotsalainen, Anna-Kaisa, et al.
Publicado: (2021)

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
por: Gerhardt, Holger, et al.
Publicado: (2003)

Building blood vessels—stem cell models in vascular biology
por: Jakobsson, Lars, et al.
Publicado: (2007)

Epigenetic Regulation of Vascular Smooth Muscle Cell Phenotype Switching in Atherosclerotic Artery Remodeling: A Mini-Review
por: Zurek, Michelle, et al.
Publicado: (2021)

Lack of cardiac and high-fat diet induced metabolic phenotypes in two independent strains of Vegf-b knockout mice
por: Dijkstra, M. H., et al.
Publicado: (2014)

Differential Regulation of Vascular Endothelial Growth Factors by Promoter-targeted shRNAs
por: Laham-Karam, Nihay, et al.
Publicado: (2015)

Editorial: Vascularization for Regenerative Medicine
por: Banfi, Andrea, et al.
Publicado: (2018)

Experimental Evaluation of an Interferometric Light Microscopy Particle Counter for Titering and Characterization of Virus Preparations
por: Turkki, Vesa, et al.
Publicado: (2021)

Adenoviral Gene Therapy Vectors in Clinical Use—Basic Aspects with a Special Reference to Replication-Competent Adenovirus Formation and Its Impact on Clinical Safety
por: Leikas, Aleksi J., et al.
Publicado: (2023)

Effects of Angiopoietin-2-Blocking Antibody on Endothelial Cell–Cell Junctions and Lung Metastasis
por: Holopainen, Tanja, et al.
Publicado: (2012)

Snake venom VEGF Vammin induces a highly efficient angiogenic response in skeletal muscle via VEGFR-2/NRP specific signaling
por: Toivanen, Pyry I., et al.
Publicado: (2017)

VEGF-C promotes the development of lymphatics in bone and bone loss
por: Hominick, Devon, et al.
Publicado: (2018)

Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart
por: Gallini, Radiosa, et al.
Publicado: (2016)

Human Vascular Endothelial Growth Factor A(165) Expression Induces the Mouse Model of Neovascular Age-Related Macular Degeneration
por: Kokki, Emmi, et al.
Publicado: (2018)

Novel Designed Proteolytically Resistant VEGF-B186R127S Promotes Angiogenesis in Mouse Heart by Recruiting Endothelial Progenitor Cells
por: Mallick, Rahul, et al.
Publicado: (2022)

Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer
por: Sallinen, Hanna, et al.
Publicado: (2014)

Intracardiac injection of a capsid-modified Ad5/35 results in decreased heart toxicity when compared to standard Ad5
por: Toivonen, Raine, et al.
Publicado: (2012)

AAV8-mediated sVEGFR2 and sVEGFR3 gene therapy combined with chemotherapy reduces the growth and microvasculature of human ovarian cancer and prolongs the survival in mice
por: Kujala, Anni, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ud72slom5n08ijc83o20mvv6a5