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Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients
BACKGROUND: The endocannabinoids, anandamide and 2-AG, are produced by adipocytes, where they stimulate lipogenesis via cannabinoid CB(1 )receptors and are under the negative control of leptin and insulin. Endocannabinoid levels are elevated in the blood of obese individuals and nonobese type 2 diab...
Autores principales: | Annuzzi, Giovanni, Piscitelli, Fabiana, Di Marino, Lucrezia, Patti, Lidia, Giacco, Rosalba, Costabile, Giuseppina, Bozzetto, Lutgarda, Riccardi, Gabriele, Verde, Roberta, Petrosino, Stefania, Rivellese, Angela A, Di Marzo, Vincenzo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868848/ https://www.ncbi.nlm.nih.gov/pubmed/20426869 http://dx.doi.org/10.1186/1476-511X-9-43 |
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