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The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs

BACKGROUND: Infected humans make protective antibody responses to the PfEMP1 adhesion antigens exported by Plasmodium falciparum parasites to the erythrocyte membrane, but little is known about the kinetics of this antibody-receptor binding reaction or how the topology of PfEMP1 on the parasitized e...

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Detalles Bibliográficos
Autores principales:	Joergensen, Lars M, Salanti, Ali, Dobrilovic, Tina, Barfod, Lea, Hassenkam, Tue, Theander, Thor G, Hviid, Lars, Arnot, David E
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868858/ https://www.ncbi.nlm.nih.gov/pubmed/20403153 http://dx.doi.org/10.1186/1475-2875-9-100

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