Effects of the NUP98-DDX10 oncogene on primary human CD34+ cells: Role of a conserved helicase motif

NUP98 gene rearrangements occur in acute myeloid leukemia and result in the expression of fusion proteins. One of the most frequent is NUP98-DDX10 that fuses a portion of NUP98 to a portion of DDX10, a putative DEAD-box RNA helicase. Here we show that NUP98-DDX10 dramatically increases proliferation...

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Detalles Bibliográficos
Autores principales: Yassin, Enas R., Abdul-Nabi, Anmaar M., Takeda, Akiko, Yaseen, Nabeel R.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868946/
https://www.ncbi.nlm.nih.gov/pubmed/20339440
http://dx.doi.org/10.1038/leu.2010.42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868946/
https://www.ncbi.nlm.nih.gov/pubmed/20339440
http://dx.doi.org/10.1038/leu.2010.42

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