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Effects of the NUP98-DDX10 oncogene on primary human CD34+ cells: Role of a conserved helicase motif

NUP98 gene rearrangements occur in acute myeloid leukemia and result in the expression of fusion proteins. One of the most frequent is NUP98-DDX10 that fuses a portion of NUP98 to a portion of DDX10, a putative DEAD-box RNA helicase. Here we show that NUP98-DDX10 dramatically increases proliferation...

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Detalles Bibliográficos
Autores principales:	Yassin, Enas R., Abdul-Nabi, Anmaar M., Takeda, Akiko, Yaseen, Nabeel R.
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868946/ https://www.ncbi.nlm.nih.gov/pubmed/20339440 http://dx.doi.org/10.1038/leu.2010.42

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